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1.
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 534-536, 2015.
Article in Chinese | WPRIM | ID: wpr-297391

ABSTRACT

<p><b>OBJECTIVE</b>To explore the effect of Peitu Shengjin Recipe (PSR) on nutritional states and immune functions of stable phase chronic obstructive pulmonary disease (COPD) patients.</p><p><b>METHODS</b>Totally 62 stable phase COPD patients were randomly assigned to the treatment group (30 cases) and the control group (32 cases). All patients inhaled Seretide (50/500 µg), twice per day. Besides, patients in the treatment group additionally received PSR, one dose per day. After three months of treatment, the COPD assessment test (CAT) score, the index of nutritional states [including body mass index (BMI) , thickness of skin fold (TSF), mid-arm muscle circumference (MAMC), serum albumin, serum prealbumin], and immune functions (including IgA, IgM, and IgG) were compared between the two groups.</p><p><b>RESULTS</b>By the end of the treatment, the CAT score decreased more obviously in the treatment group than in the control group (P < 0.05). The improvement of BMI, TSF, MAMC, serum albumin, and serum prealbumin was better in the treatment group than in the control group (P < 0.05). IgM and IgG also increased more in the treatment group (P < 0.05). There was no statistical difference in IgA between the two groups (P > 0.05).</p><p><b>CONCLUSIONS</b>Additionally use of PSR could improve nutritional states and immune functions of stable phase COPD patients to some extent. Meanwhile, it also could improve their health related quality of life.</p>


Subject(s)
Humans , Body Mass Index , Drugs, Chinese Herbal , Therapeutic Uses , Nutritional Status , Pulmonary Disease, Chronic Obstructive , Drug Therapy , Allergy and Immunology , Quality of Life , Serum Albumin
2.
Chinese Journal of Integrated Traditional and Western Medicine ; (12): 673-675, 2003.
Article in Chinese | WPRIM | ID: wpr-240890

ABSTRACT

<p><b>OBJECTIVE</b>To observe the therapeutic effect of Zhifeng Huatan Pingxiao recipe (ZHPR) in treating attack stage of child asthma.</p><p><b>METHODS</b>Sixty child asthma patients with attack of mild and moderate degree were randomly divided into the treated group (40 patients treated with ZHPR) and the control group (20 patients treated with western medicine). The therapeutic effect and laboratory indexes, including peripheral eosinophil count (EOS), serum immunoglobulin E (IgE) and plasma endothelin (ET), before and after treatment were observed.</p><p><b>RESULTS</b>The total effective rate in the treated group was 72.5%, which was not different to that in the control group (P > 0.05). The therapeutic effect between different TCM types (heat and cold types) in the treated group was not different significantly (P > 0.05). ET, IgE and EOS levels all lowered after treatment in the treated group, but as compared with those in the control group, the difference was insignificant (P > 0.05).</p><p><b>CONCLUSION</b>The therapeutic effect of ZHPR in treating child asthma attack stage is equivalent to that of western medicine, it shows actions in improving laboratory indexes.</p>


Subject(s)
Adolescent , Child , Child, Preschool , Female , Humans , Male , Asthma , Blood , Drug Therapy , Drugs, Chinese Herbal , Therapeutic Uses , Endothelins , Blood , Eosinophils , Immunoglobulin E , Blood , Leukocyte Count , Phytotherapy
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